Overview

Parasites are any of a number of worms or microscopic organisms that can infect humans. Many are transmitted by ingestion of contaminated food or water, although other modes of transmission are also possible.

Parasites are made up of eukaryotic cells similar to their human hosts, in contrast to bacteria that have distinctly different cells. This makes treatment of parasitic infections harder than the treatment of bacterial infections, since it is harder to find chemical agents that are toxic to the infective agent without also being toxic to the human host.

Many species of parasites are uncommon in North American populations but common in third world countries where sanitary conditions are poorer. However, with increased international travel, many parasites previously associated only with third world countries are showing up in North America, requiring a higher level of suspicion of parasites than in years past.

Please see conventional, complimentary and alternative medical treatments for important background information regarding the different types of medical treatments discussed on this page. Naturopathic, Complimentary and Alternative treatments that may be considered include:


Signs and Symptoms

  • Gastrointestinal pain
  • Diarrhea
  • Nausea / reduced food intake
  • Pruritus ani (especially pinworm)
  • Intestinal obstruction (especially roundworm)
  • Appendicitis (especially roundworm)
  • Intestinal bleeding and anemia
  • Malabsorption of nutrients and micronutrients
  • Retardation of growth and cognitive development
  • Surgical complications such as obstruction, rectal prolapse and abscess

Diagnosis

Isolation of parasites or their eggs (ova) from the patient's feces is the gold standard in diagnosing parasites. However, due to the complex life-cycles of many parasites, it is easy to fail to find parasites or ova in a single sample. For this reason, at least three samples are generally collected.

Colonoscopy and biopsy.


Differential Diagnosis


Treatment

Reinfection is common in many parasitic infestations; therefore, all members of the household should be treated, and good hygiene is a must.
  • Pinworm (Enterobius vermicularis): Pyrantel pamoate, albendazole, mebendazole. Clean bed linens and house daily during treatment [Tabers2013].
  • Roundworm (Ascaris lumbricoides): Pyrantel pamoate is the drug of choice, mebendazole is also effective [Tabers2013].
  • Hookworm (Necator americanus, Ancylostomia duodenale, Strongyloides): Mebendazole, pyrantel pamoate. Iron supplementation for anemia [Tabers2013].
  • Balantidium coli: Tetracyclines, metronidazole, paromomycin [Tabers2013].
  • Entamoeba histolytica: Asymptomatic patients: paromomycin (500mg PO TID for 7 days) or iodoquinol (650mg PO TID for 20 days). Dysentery and liver abscesses are treated with metronidazole (750mg PO TID for 10 days) followed by iodoquinol (650mg PO TID for 20 days) [Tabers2013].
  • Giardia lamblia: Metronidazole, albendazole [Tabers2013].
  • Strongyloides stercoralis: Thiabendazole or mebendazole. Repeated courses of treatment may be necessary [Tabers2013].
  • Tapeworm (Taenia spp., Diphyllobothrium latum, Hymenolepis spp., Echinococcus granulosus:
  • Trichinella spiralis):
  • Whipworm (Trichuris trichiura): Mebendazole is drug of choice, albendazole, ivermectin also useful [Tabers2013].
  • Liver Fluke (Fasciola hepatica):
  • Lung Fluke (Paragonimus spp.):

Prevention

Improved sanitation, hygiene, boiling water, adequately cooking foods.

References